{"id":3132,"date":"2025-06-10T19:01:10","date_gmt":"2025-06-10T10:01:10","guid":{"rendered":"https:\/\/best-biostatistics.com\/toukei-er\/?p=3132"},"modified":"2025-06-14T08:33:23","modified_gmt":"2025-06-13T23:33:23","slug":"sensitivity-specificity-analysis-sample-size-calculation-method","status":"publish","type":"post","link":"https:\/\/best-biostatistics.com\/toukei-er\/entry\/sensitivity-specificity-analysis-sample-size-calculation-method\/","title":{"rendered":"R \u3067\u611f\u5ea6\u30fb\u7279\u7570\u5ea6\u5206\u6790\u306b\u5fc5\u8981\u306a\u30b5\u30f3\u30d7\u30eb\u6570\u3092\u8a08\u7b97\u3059\u308b\u65b9\u6cd5"},"content":{"rendered":"\n<p>\u8a3a\u65ad\u691c\u67fb\u306e\u611f\u5ea6\u30fb\u7279\u7570\u5ea6\u5206\u6790\u306b\u304a\u3051\u308b\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u8a08\u7b97\u306f\u3001\u7814\u7a76\u306e\u76ee\u7684\u3001\u75be\u60a3\u6709\u75c5\u7387\u3001\u671f\u5f85\u3055\u308c\u308b\u611f\u5ea6\u30fb\u7279\u7570\u5ea6\u3001\u8a31\u5bb9\u8aa4\u5dee\u3001\u691c\u51fa\u529b\u306b\u57fa\u3065\u3044\u3066\u884c\u308f\u308c\u308b\u3002\u5c0f\u3055\u3059\u304e\u308b\u3068\u4fe1\u983c\u6027\u304c\u4f4e\u304f\u3001\u5927\u304d\u3059\u304e\u308b\u3068\u30ea\u30bd\u30fc\u30b9\u304c\u7121\u99c4\u306b\u306a\u308b\u3002\u7d71\u8a08\u7684\u306b\u4fe1\u983c\u3067\u304d\u308b\u7d50\u679c\u3092\u5f97\u308b\u306b\u306f\u3001\u3053\u308c\u3089\u306e\u8981\u7d20\u3092\u8003\u616e\u3057\u3001\u9069\u5207\u306a\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3092\u6c7a\u5b9a\u3059\u308b\u3053\u3068\u304c\u4e0d\u53ef\u6b20\u3067\u3042\u308b\u3002<\/p>\n\n\n\n<!--more-->\n\n\n\n<h2 class=\"wp-block-heading\">\u8a3a\u65ad\u691c\u67fb\u306e\u611f\u5ea6\u30fb\u7279\u7570\u5ea6\u5206\u6790\u306b\u304a\u3051\u308b\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u8a08\u7b97\u306e\u67a0\u7d44\u307f<\/h2>\n\n\n\n<p><br>\u8a3a\u65ad\u691c\u67fb\u306e\u611f\u5ea6\u30fb\u7279\u7570\u5ea6\u5206\u6790\u306b\u304a\u3051\u308b\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u8a08\u7b97\u306e\u67a0\u7d44\u307f\u306f\u3001\u4e3b\u306b\u5358\u4e00\u306e\u611f\u5ea6\u30fb\u7279\u7570\u5ea6\u3092\u63a8\u5b9a\u3059\u308b\u5834\u5408\u3068\u3001\u8907\u6570\u306e\u691c\u67fb\u306e\u611f\u5ea6\u30fb\u7279\u7570\u5ea6\u3092\u6bd4\u8f03\u3059\u308b\u5834\u5408\u306b\u5206\u3051\u3089\u308c\u308b\u3002<\/p>\n\n\n\n<p>\u5358\u4e00\u63a8\u5b9a\u306e\u5834\u5408\u3001\u76ee\u6a19\u3068\u3059\u308b\u611f\u5ea6\u307e\u305f\u306f\u7279\u7570\u5ea6\u306e\u5024\u3092\u3042\u308b\u300c\u8a31\u5bb9\u3055\u308c\u308b\u8aa4\u5dee\u300d\uff08\u4f8b\uff1a95%\u4fe1\u983c\u533a\u9593\u306e\u5e45\uff09\u3067\u63a8\u5b9a\u3059\u308b\u305f\u3081\u306b\u5fc5\u8981\u306a\u75c7\u4f8b\u6570\u3092\u7b97\u51fa\u3059\u308b\u3002\u3053\u306e\u969b\u3001\u63a8\u5b9a\u3059\u308b\u5024\u3068\u8aa4\u5dee\u306e\u8a31\u5bb9\u7bc4\u56f2\u3092\u8a2d\u5b9a\u3059\u308b\u3002<\/p>\n\n\n\n<p>\u6bd4\u8f03\u306e\u5834\u5408\u3001\u7279\u5b9a\u306e\u5dee\uff08\u4f8b\uff1a\u611f\u5ea610%\u306e\u5dee\uff09\u3092\u300c\u7d71\u8a08\u7684\u691c\u51fa\u529b\u300d\uff08\u901a\u5e3880%\u4ee5\u4e0a\uff09\u3068\u300c\u6709\u610f\u6c34\u6e96\u300d\uff08\u901a\u5e380.05\uff09\u3067\u691c\u51fa\u3059\u308b\u305f\u3081\u306b\u5fc5\u8981\u306a\u75c7\u4f8b\u6570\u3092\u7b97\u51fa\u3059\u308b\u3002<\/p>\n\n\n\n<p>\u3044\u305a\u308c\u306e\u67a0\u7d44\u307f\u3067\u3082\u5fc5\u8981\u3068\u306a\u308b\u4e3b\u306a\u5024\u306f\u4ee5\u4e0b\u306e\u3068\u304a\u308a\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li> \u671f\u5f85\u3055\u308c\u308b\u611f\u5ea6\u30fb\u7279\u7570\u5ea6: \u5148\u884c\u7814\u7a76\u3084\u4e88\u5099\u30c7\u30fc\u30bf\u306b\u57fa\u3065\u304f\u63a8\u5b9a\u5024<\/li>\n\n\n\n<li> \u5bfe\u8c61\u75be\u60a3\u306e\u6709\u75c5\u7387: \u96c6\u56e3\u306b\u304a\u3051\u308b\u75be\u60a3\u306e\u5272\u5408<\/li>\n\n\n\n<li> \u8a31\u5bb9\u3055\u308c\u308b\u8aa4\u5dee\uff08\u7cbe\u5ea6\uff09: \u63a8\u5b9a\u5024\u306e\u4fe1\u983c\u533a\u9593\u306e\u5e45<\/li>\n\n\n\n<li> \u7d71\u8a08\u7684\u691c\u51fa\u529b\uff081 &#8211; \u03b2\uff09: \u771f\u306e\u5dee\u3092\u691c\u51fa\u3067\u304d\u308b\u78ba\u7387<\/li>\n\n\n\n<li> \u6709\u610f\u6c34\u6e96 (\u03b1): \u507d\u967d\u6027\u3092\u8a31\u5bb9\u3059\u308b\u78ba\u7387<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u5024\u3092\u9069\u5207\u306b\u8a2d\u5b9a\u3059\u308b\u3053\u3068\u3067\u3001\u7d71\u8a08\u7684\u306b\u4fe1\u983c\u3067\u304d\u308b\u7d50\u679c\u3092\u5f97\u308b\u305f\u3081\u306e\u9069\u5207\u306a\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u304c\u5c0e\u304d\u51fa\u3055\u308c\u308b\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u611f\u5ea6\u307e\u305f\u306f\u7279\u7570\u5ea6\u5358\u4e00\u5024\u3092\u63a8\u5b9a\u3059\u308b\u5834\u5408<\/h2>\n\n\n\n<p>R\u8a00\u8a9e\u3067\u3001\u5358\u4e00\u306e\u611f\u5ea6\u307e\u305f\u306f\u7279\u7570\u5ea6\u3092\u63a8\u5b9a\u3059\u308b\u5834\u5408\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u8a08\u7b97\u306f\u3001\u57fa\u672c\u7684\u306b\u4e8c\u9805\u5206\u5e03\u306e\u4fe1\u983c\u533a\u9593\u306e\u5e45\u3092\u57fa\u306b\u9006\u7b97\u3059\u308b\u5f62\u3067\u884c\u308f\u308c\u308b\u3002\u7279\u5b9a\u306e\u5272\u5408\uff08\u611f\u5ea6\u3084\u7279\u7570\u5ea6\uff09\u3092\u3001\u6307\u5b9a\u3057\u305f\u4fe1\u983c\u5ea6\uff08\u4f8b\uff1a95%\uff09\u3068\u8a31\u5bb9\u8aa4\u5dee\uff08\u4fe1\u983c\u533a\u9593\u306e\u534a\u5206\u306e\u5e45\uff09\u3067\u63a8\u5b9a\u3059\u308b\u305f\u3081\u306b\u5fc5\u8981\u306a\u75c7\u4f8b\u6570\u3092\u6c42\u3081\u308b\u3002<\/p>\n\n\n\n<p>presize \u30d1\u30c3\u30b1\u30fc\u30b8\u306e prec_prop \u95a2\u6570\u3092\u7528\u3044\u308b\u306e\u304c\u4fbf\u5229\u3067\u3042\u308b\u3002\u3053\u306e\u95a2\u6570\u306f\u3001\u5272\u5408\u306e\u4fe1\u983c\u533a\u9593\u306e\u5e45\u304b\u3089\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3092\u8a08\u7b97\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u611f\u5ea6\u3092\u63a8\u5b9a\u3059\u308b\u5834\u5408\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u8a08\u7b97\u4f8b<\/h3>\n\n\n\n<p><br>\u611f\u5ea6\u3092\u63a8\u5b9a\u3059\u308b\u5834\u5408\u3001\u75be\u60a3\u306e\u3042\u308b\u88ab\u9a13\u8005\uff08\u771f\u306e\u967d\u6027\u3001\u507d\u9670\u6027\uff09\u306e\u6570\u304c\u5fc5\u8981\u3002<\/p>\n\n\n\n<p><br>\u30b7\u30ca\u30ea\u30aa\u4f8b:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u671f\u5f85\u3055\u308c\u308b\u611f\u5ea6: 90% (0.90)<\/li>\n\n\n\n<li>\u8a31\u5bb9\u3055\u308c\u308b\u4fe1\u983c\u533a\u9593\u306e\u534a\u5206\u306e\u5e45 (precision): \u00b15% (0.05)<\/li>\n\n\n\n<li>\u4fe1\u983c\u6c34\u6e96: 95% (0.95)<\/li>\n<\/ul>\n\n\n\n<pre class=\"wp-block-code\"><code># presize \u30d1\u30c3\u30b1\u30fc\u30b8\u3092\u30a4\u30f3\u30b9\u30c8\u30fc\u30eb\u3057\u3066\u3044\u306a\u3044\u5834\u5408\u306f\u30a4\u30f3\u30b9\u30c8\u30fc\u30eb\n# install.packages(\"presize\")\n\nlibrary(presize)\n\n# \u611f\u5ea6\u3092\u63a8\u5b9a\u3059\u308b\u305f\u3081\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u8a08\u7b97\n# p: \u671f\u5f85\u3055\u308c\u308b\u611f\u5ea6\uff08\u5272\u5408\uff09\n# conf.width: \u4fe1\u983c\u533a\u9593\u306e\u5168\u5e45 (\u4f8b: 0.10 \u306f \u00b10.05 \u3092\u610f\u5473\u3059\u308b)\n# conf.level: \u4fe1\u983c\u6c34\u6e96\n\n# \u30b7\u30ca\u30ea\u30aa1: \u611f\u5ea6 90% \u3092 \u00b15% \u306e\u7cbe\u5ea6 (\u5168\u5e45 10%) \u3067\u63a8\u5b9a\u3057\u305f\u3044\u5834\u5408\n# \u3053\u3053\u3067\u5f97\u3089\u308c\u308b 'n' \u306f\u3001\u300c\u75be\u60a3\u3092\u6301\u3064\u4eba\u300d\u306e\u5fc5\u8981\u306a\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3067\u3059\u3002\nn_sensitivity &lt;- prec_prop(p = 0.90, conf.width = 0.10, conf.level = 0.95, method = \"wilson\")\n\nprint(n_sensitivity)\n\n# \u7d50\u679c\u306e\u89e3\u91c8\n# $n: \u5fc5\u8981\u306a\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\uff08\u75be\u60a3\u3092\u6301\u3064\u4eba\u306e\u6570\uff09\n# $p_adj: Wilson\u6cd5\u3067\u8abf\u6574\u3055\u308c\u305f\u5272\u5408\n# $conf.width: \u8a2d\u5b9a\u3057\u305f\u4fe1\u983c\u533a\u9593\u306e\u5168\u5e45\n# $conf.level: \u8a2d\u5b9a\u3057\u305f\u4fe1\u983c\u6c34\u6e96\n# note: \u4f7f\u7528\u3057\u305f\u8a08\u7b97\u65b9\u6cd5\u306b\u95a2\u3059\u308b\u6ce8\u610f<\/code><\/pre>\n\n\n\n<p>\u8a08\u7b97\u3059\u308b\u3068\u3001141 \u4eba\uff08140.9728 \u3092\u5207\u308a\u4e0a\u3052\u3066 141\uff09\u5fc5\u8981\u3067\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u308b\u3002<\/p>\n\n\n\n<pre class=\"wp-block-code\"><code>> print(n_sensitivity)\n\n     sample size for a proportion with Wilson confidence interval. \n\n    p      padj        n conf.width conf.level       lwr       upr\n1 0.9 0.8893893 140.9728        0.1       0.95 0.8393893 0.9393893\n\nNOTE: padj is the adjusted proportion, from which the ci is calculated.<\/code><\/pre>\n\n\n\n<h3 class=\"wp-block-heading\">\u7279\u7570\u5ea6\u3092\u63a8\u5b9a\u3059\u308b\u5834\u5408\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u8a08\u7b97\u4f8b<\/h3>\n\n\n\n<p>\u7279\u7570\u5ea6\u3092\u63a8\u5b9a\u3059\u308b\u5834\u5408\u3001\u75be\u60a3\u306e\u306a\u3044\u88ab\u9a13\u8005\uff08\u771f\u306e\u9670\u6027\u3001\u507d\u967d\u6027\uff09\u306e\u6570\u304c\u5fc5\u8981\u3002<\/p>\n\n\n\n<p><br>\u30b7\u30ca\u30ea\u30aa\u4f8b:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u671f\u5f85\u3055\u308c\u308b\u7279\u7570\u5ea6: 80% (0.80)<\/li>\n\n\n\n<li>\u8a31\u5bb9\u3055\u308c\u308b\u4fe1\u983c\u533a\u9593\u306e\u534a\u5206\u306e\u5e45 (precision): \u00b17% (0.07)<\/li>\n\n\n\n<li>\u4fe1\u983c\u6c34\u6e96: 95% (0.95)<\/li>\n<\/ul>\n\n\n\n<pre class=\"wp-block-code\"><code># \u7279\u7570\u5ea6\u3092\u63a8\u5b9a\u3059\u308b\u305f\u3081\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u8a08\u7b97\n# p: \u671f\u5f85\u3055\u308c\u308b\u7279\u7570\u5ea6\uff08\u5272\u5408\uff09\n# conf.width: \u4fe1\u983c\u533a\u9593\u306e\u5168\u5e45 (\u4f8b: 0.14 \u306f \u00b10.07 \u3092\u610f\u5473\u3059\u308b)\n\n# \u30b7\u30ca\u30ea\u30aa2: \u7279\u7570\u5ea6 80% \u3092 \u00b17% \u306e\u7cbe\u5ea6 (\u5168\u5e45 14%) \u3067\u63a8\u5b9a\u3057\u305f\u3044\u5834\u5408\n# \u3053\u3053\u3067\u5f97\u3089\u308c\u308b 'n' \u306f\u3001\u300c\u75be\u60a3\u3092\u6301\u305f\u306a\u3044\u4eba\u300d\u306e\u5fc5\u8981\u306a\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3067\u3059\u3002\nn_specificity &lt;- prec_prop(p = 0.80, conf.width = 0.14, conf.level = 0.95, method = \"wilson\")\n\nprint(n_specificity)\n<\/code><\/pre>\n\n\n\n<p>\u8a08\u7b97\u7d50\u679c\u306f\u3001124 \u4eba\uff08123.7188 \u3092\u5207\u308a\u4e0a\u3052\u3066 124\uff09\u3067\u3042\u308b\u3002<\/p>\n\n\n\n<pre class=\"wp-block-code\"><code>> print(n_specificity)\n\n     sample size for a proportion with Wilson confidence interval. \n\n    p      padj        n conf.width conf.level       lwr       upr\n1 0.8 0.7909655 123.7188       0.14       0.95 0.7209655 0.8609655\n\nNOTE: padj is the adjusted proportion, from which the ci is calculated.<\/code><\/pre>\n\n\n\n<h3 class=\"wp-block-heading\">\u7dcf\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u306e\u7b97\u51fa<\/h3>\n\n\n\n<p>\u4e0a\u8a18\u306e\u8a08\u7b97\u3067\u5f97\u3089\u308c\u308b n \u306f\u3001\u305d\u308c\u305e\u308c\u300c\u75be\u60a3\u3092\u6301\u3064\u4eba\u300d\u3068\u300c\u75be\u60a3\u3092\u6301\u305f\u306a\u3044\u4eba\u300d\u306e\u5fc5\u8981\u306a\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3067\u3042\u308b\u3002\u7814\u7a76\u5168\u4f53\u306e\u7dcf\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3092\u6c7a\u5b9a\u3059\u308b\u306b\u306f\u3001\u5bfe\u8c61\u96c6\u56e3\u306b\u304a\u3051\u308b\u75be\u60a3\u306e\u6709\u75c5\u7387\uff08Prevalence\uff09\u3092\u8003\u616e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002<\/p>\n\n\n\n<p><br>\u7dcf\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba N \u306f\u3001\u4ee5\u4e0b\u306e\u95a2\u4fc2\u3067\u7b97\u51fa\u3067\u304d\u308b\u3002<\/p>\n\n\n\n\n\n\n\n<p>$$ \\begin{array} {rcl} N &amp;=&amp; \\text{\u5fc5\u8981\u306a\u75be\u60a3\u6709\u308a\u306e\u4eba\u6570} \/ \\text{\u6709\u75c5\u7387} \\\\<br>N &amp;=&amp; \\text{\u5fc5\u8981\u306a\u75be\u60a3\u7121\u3057\u306e\u4eba\u6570} \/ (1 &#8211; \\text{\u6709\u75c5\u7387}) \\end{array} $$<\/p>\n\n\n\n<p>\u3088\u308a\u53b3\u5bc6\u306b\u306f\u3001\u611f\u5ea6\u3068\u7279\u7570\u5ea6\u306e\u4e21\u65b9\u3092\u3042\u308b\u7a0b\u5ea6\u306e\u7cbe\u5ea6\u3067\u63a8\u5b9a\u3057\u305f\u3044\u5834\u5408\u3001\u4e21\u65b9\u306e\u6761\u4ef6\u3092\u6e80\u305f\u3059\u3088\u3046\u306b\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3092\u8a2d\u5b9a\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002\u4e00\u822c\u7684\u306b\u306f\u3001\u305d\u308c\u305e\u308c\u3067\u7b97\u51fa\u3055\u308c\u305f\u300c\u75be\u60a3\u306e\u3042\u308b\u88ab\u9a13\u8005\u300d\u3068\u300c\u75be\u60a3\u306e\u306a\u3044\u88ab\u9a13\u8005\u300d\u306e\u5fc5\u8981\u306a\u6570\u3092\u5408\u8a08\u3057\u3001\u6709\u75c5\u7387\u3092\u8003\u616e\u3057\u3066\u8abf\u6574\u3059\u308b\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u75be\u60a3\u306e\u3042\u308b\u88ab\u9a13\u8005\u304c 141 \u4eba\u3001\u75be\u60a3\u306e\u306a\u3044\u88ab\u9a13\u8005\u304c 124 \u4eba\u5fc5\u8981\u3067\u3001\u6709\u75c5\u7387\u304c20%\u306e\u5834\u5408\u3001\u7dcf\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u306b\u8a08\u7b97\u3055\u308c\u308b\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li> \u75be\u60a3\u306e\u3042\u308b\u88ab\u9a13\u8005\u306e\u78ba\u4fdd\u306b\u5fc5\u8981\u306a\u7dcf\u6570 = 141 \/ 0.20 = 705 \u4eba<\/li>\n\n\n\n<li> \u75be\u60a3\u306e\u306a\u3044\u88ab\u9a13\u8005\u306e\u78ba\u4fdd\u306b\u5fc5\u8981\u306a\u7dcf\u6570 = 124 \/ (1 &#8211; 0.20) = 155 \u4eba<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u5834\u5408\u3001\u4e21\u65b9\u306e\u6761\u4ef6\u3092\u6e80\u305f\u3059\u306b\u306f\u3001\u3088\u308a\u5927\u304d\u3044\u65b9\u306e\u4eba\u6570\u3001\u3064\u307e\u308a 705 \u4eba\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u304c\u5fc5\u8981\u306b\u306a\u308b\u3002<\/p>\n\n\n\n<p><strong>\u91cd\u8981\u306a\u6ce8\u610f\u70b9:<\/strong><br>\u75be\u60a3\u306e\u6709\u75c5\u7387\u304c\u975e\u5e38\u306b\u4f4e\u3044\u5834\u5408\u3001\u75be\u60a3\u3092\u6301\u3064\u60a3\u8005\u3055\u3093\u3092\u5341\u5206\u306b\u96c6\u3081\u308b\u3053\u3068\u304c\u56f0\u96e3\u306b\u306a\u308b\u305f\u3081\u3001\u975e\u5bfe\u79f0\u306a\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\uff08\u75be\u60a3\u306e\u3042\u308b\u60a3\u8005\u3092\u591a\u3081\u306b\u96c6\u3081\u308b\u306a\u3069\uff09\u3092\u691c\u8a0e\u3059\u308b\u3053\u3068\u3082\u3042\u308b\u3002<\/p>\n\n\n\n<div id=\"biost-2366142722\" class=\"biost- biost-entity-placement\"><p style=\"text-align: center;\"><span style=\"font-size: 20px;\"><strong><a href=\"https:\/\/best-biostatistics.com\/kmhl\">\uff1e\uff1e\u3082\u3046\u7d71\u8a08\u3067\u60a9\u3080\u306e\u306f\u7d42\u308f\u308a\u306b\u3057\u307e\u305b\u3093\u304b\uff1f\u00a0<\/a><\/strong><\/span><\/p>\r\n<a href=\"https:\/\/best-biostatistics.com\/kmhl\"><img class=\"aligncenter wp-image-2794 size-full\" src=\"https:\/\/best-biostatistics.com\/wp\/wp-content\/uploads\/2023\/11\/bn_r_03.png\" alt=\"\" width=\"500\" height=\"327\" \/><\/a>\r\n<p style=\"text-align: center;\"><span style=\"color: #ff0000; font-size: 20px;\"><strong><span class=\"marker2\">\u21911\u4e07\u4eba\u4ee5\u4e0a\u306e\u533b\u7642\u5f93\u4e8b\u8005\u304c\u8cfc\u8aad\u4e2d<\/span><\/strong><\/span><\/p><\/div><h2 class=\"wp-block-heading\">\u611f\u5ea6\u307e\u305f\u306f\u7279\u7570\u5ea6\u3092\u6bd4\u8f03\u3059\u308b\u5834\u5408<\/h2>\n\n\n\n<p>\u8a3a\u65ad\u691c\u67fb\u306e\u611f\u5ea6\u3084\u7279\u7570\u5ea6\u3092\u6bd4\u8f03\u3059\u308b\u5834\u5408\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u8a08\u7b97\u306f\u30012\u3064\u306e\u5272\u5408\uff08\u6bd4\u7387\uff09\u306e\u5dee\u306e\u691c\u5b9a\u306b\u57fa\u3065\u304f\u3053\u3068\u304c\u4e00\u822c\u7684\u3067\u3042\u308b\u3002\u3053\u308c\u306f\u3001\u65b0\u3057\u3044\u8a3a\u65ad\u691c\u67fb\u306e\u6027\u80fd\u304c\u65e2\u5b58\u306e\u691c\u67fb\u3088\u308a\u3082\u512a\u308c\u3066\u3044\u308b\u304b\u3001\u307e\u305f\u306f\u540c\u7b49\u3067\u3042\u308b\u304b\u3092\u7d71\u8a08\u7684\u306b\u691c\u8a3c\u3057\u305f\u3044\u5834\u5408\u306b\u7528\u3044\u3089\u308c\u308b\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u5834\u5408\u3001R \u306e pwr \u30d1\u30c3\u30b1\u30fc\u30b8\u306e pwr.2p.test \u95a2\u6570\u3092\u4f7f\u3046\u306e\u304c\u4fbf\u5229\u3067\u3042\u308b\u3002\u3053\u306e\u95a2\u6570\u306f\u30012\u3064\u306e\u72ec\u7acb\u3057\u305f\u6bd4\u7387\u306e\u5dee\u3092\u691c\u5b9a\u3059\u308b\u305f\u3081\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3084\u691c\u51fa\u529b\u3092\u8a08\u7b97\u3067\u304d\u308b\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u6bd4\u8f03\u306e\u30b7\u30ca\u30ea\u30aa1: \u611f\u5ea6\u306e\u6bd4\u8f03\uff08\u75be\u60a3\u3042\u308a\u306e\u88ab\u9a13\u8005\u3067\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\uff09<\/h3>\n\n\n\n<p>\u3053\u3053\u3067\u306f\u30012\u3064\u306e\u8a3a\u65ad\u691c\u67fb\u306e\u611f\u5ea6\u3092\u6bd4\u8f03\u3059\u308b\u4f8b\u3092\u793a\u3059\u3002\u7279\u7570\u5ea6\u3092\u6bd4\u8f03\u3059\u308b\u5834\u5408\u3082\u540c\u69d8\u306e\u8003\u3048\u65b9\u3067\u9069\u7528\u3067\u304d\u308b\u3002<\/p>\n\n\n\n<p>\u30b7\u30ca\u30ea\u30aa:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u691c\u67fbA\uff08\u65e2\u5b58\u306e\u6a19\u6e96\u691c\u67fb\uff09\u306e\u671f\u5f85\u3055\u308c\u308b\u611f\u5ea6: P_1 = 0.70 (70%)<\/li>\n\n\n\n<li>\u691c\u67fbB\uff08\u65b0\u3057\u3044\u691c\u67fb\uff09\u306e\u671f\u5f85\u3055\u308c\u308b\u611f\u5ea6: P_2 = 0.85 (85%)<\/li>\n\n\n\n<li>\u691c\u51fa\u3057\u305f\u3044\u611f\u5ea6\u306e\u5dee: 0.85 &#8211; 0.70 = 0.15 (15%)<\/li>\n\n\n\n<li>\u6709\u610f\u6c34\u6e96 (\u03b1): 0.05 (\u4e21\u5074\u691c\u5b9a)<\/li>\n\n\n\n<li>\u7d71\u8a08\u7684\u691c\u51fa\u529b (1 &#8211; \u03b2): 0.80 (80%)<\/li>\n\n\n\n<li>\u5404\u7fa4\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u6bd4: n_1 = n_2 (\u540c\u6570)<\/li>\n<\/ul>\n\n\n\n<p><br>\u3053\u306e\u8a08\u7b97\u3067\u306f\u3001\u300c\u75be\u60a3\u306e\u3042\u308b\u88ab\u9a13\u8005\u300d\u306b\u304a\u3051\u308b\u611f\u5ea6\u306e\u6bd4\u8f03\u306b\u7126\u70b9\u3092\u5f53\u3066\u3066\u3044\u308b\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u7b97\u51fa\u3055\u308c\u308b\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u306f\u3001\u75be\u60a3\u3092\u6301\u3064\u88ab\u9a13\u8005\u306e\u6570\u306b\u306a\u308b\u3002\u7dcf\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3092\u6c42\u3081\u308b\u306b\u306f\u3001\u5225\u9014\u3001\u5bfe\u8c61\u75be\u60a3\u306e\u6709\u75c5\u7387\u3092\u8003\u616e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\uff08\u5f8c\u8ff0\uff09<\/p>\n\n\n\n<p><br>R\u30b9\u30af\u30ea\u30d7\u30c8\u4f8b<\/p>\n\n\n\n<pre class=\"wp-block-code\"><code># \u6bd4\u8f03\u306e\u5834\u5408\n# pwr \u30d1\u30c3\u30b1\u30fc\u30b8\u3092\u30a4\u30f3\u30b9\u30c8\u30fc\u30eb\u3057\u3066\u3044\u306a\u3044\u5834\u5408\u306f\u30a4\u30f3\u30b9\u30c8\u30fc\u30eb\n# install.packages(\"pwr\")\n\nlibrary(pwr)\n\n# 2\u3064\u306e\u611f\u5ea6\u3092\u6bd4\u8f03\u3059\u308b\u305f\u3081\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u8a08\u7b97\n# p1: \u691c\u67fbA\u306e\u611f\u5ea6 (\u65e2\u5b58\u306e\u691c\u67fb)\n# p2: \u691c\u67fbB\u306e\u611f\u5ea6 (\u65b0\u3057\u3044\u691c\u67fb)\n# sig.level: \u6709\u610f\u6c34\u6e96 (\u03b1)\n# power: \u7d71\u8a08\u7684\u691c\u51fa\u529b (1-\u03b2)\n# alternative: \u691c\u5b9a\u306e\u7a2e\u985e (\"two.sided\", \"less\", \"greater\")\n#\u00a0\u00a0 - \"two.sided\": \u5dee\u304c\u3042\u308b\u304b\u3092\u691c\u5b9a\n#\u00a0\u00a0 - \"greater\": p2 \u304c p1 \u3088\u308a\u5927\u304d\u3044\u304b\u3092\u691c\u5b9a (\u512a\u8d8a\u6027\u8a66\u9a13)\n#\u00a0\u00a0 - \"less\": p2 \u304c p1 \u3088\u308a\u5c0f\u3055\u3044\u304b\u3092\u691c\u5b9a (\u7a00)\n\n# Effect size (h) \u306e\u8a08\u7b97\n# h = 2 * (asin(sqrt(p2)) - asin(sqrt(p1)))\nh &lt;- ES.h(p1 = 0.70, p2 = 0.85)\ncat(\"\u8a08\u7b97\u3055\u308c\u305f\u52b9\u679c\u91cf (Effect size, h):\", h, \"\\n\")\n\nn_compare_sens &lt;- pwr.2p.test(h = h, n = NULL, sig.level = 0.05, power = 0.80, alternative = \"two.sided\")\n\nprint(n_compare_sens)<\/code><\/pre>\n\n\n\n<p>\u52b9\u679c\u91cf\u304c\u3001\u7d04 -0.364 \u3068\u8a08\u7b97\u3055\u308c\u308b\u3002\u5206\u91ce\u306b\u3088\u3063\u3066\u306f\u3001\u7d71\u8a08\u89e3\u6790\u6642\u306b\u63d0\u793a\u304c\u5fc5\u8981\u306b\u306a\u308b\u6307\u6a19\u3067\u3042\u308b\u3002<\/p>\n\n\n\n<p>\u7d50\u679c\u3068\u3057\u3066\u3001119 \u4eba\u5fc5\u8981\u3068\u8a08\u7b97\u3055\u308c\u308b\u3002<\/p>\n\n\n\n<pre class=\"wp-block-code\"><code>> cat(\"\u8a08\u7b97\u3055\u308c\u305f\u52b9\u679c\u91cf (Effect size, h):\", h, \"\\n\")\n\u8a08\u7b97\u3055\u308c\u305f\u52b9\u679c\u91cf (Effect size, h): -0.3638807 \n\n> print(n_compare_sens)\n\n     Difference of proportion power calculation for binomial distribution (arcsine transformation) \n\n              h = 0.3638807\n              n = 118.5547\n      sig.level = 0.05\n          power = 0.8\n    alternative = two.sided\n\nNOTE: same sample sizes<\/code><\/pre>\n\n\n\n<h3 class=\"wp-block-heading\">\u6bd4\u8f03\u306e\u30b7\u30ca\u30ea\u30aa2: \u7279\u7570\u5ea6\u306e\u6bd4\u8f03\uff08\u75be\u60a3\u306a\u3057\u306e\u88ab\u9a13\u8005\u3067\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\uff09<\/h3>\n\n\n\n<p>\u7279\u7570\u5ea6\u306e\u6bd4\u8f03\u3082\u3001\u611f\u5ea6\u306e\u6bd4\u8f03\u3068\u540c\u69d8\u3067\u3042\u308b\u3002<\/p>\n\n\n\n<pre class=\"wp-block-code\"><code># \u7279\u7570\u5ea6\u306e\u6bd4\u8f03\n# \u7279\u7570\u5ea6 1 (Sp1): 0.75\n# \u7279\u7570\u5ea6 2 (Sp2): 0.90\n# \u4ed6\u306e\u30d1\u30e9\u30e1\u30fc\u30bf\u306f\u30b7\u30ca\u30ea\u30aa1\u3068\u540c\u3058\n\nh_spec &lt;- ES.h(p1 = 0.75, p2 = 0.90)\ncat(\"\u8a08\u7b97\u3055\u308c\u305f\u52b9\u679c\u91cf (Effect size, h):\", h_spec, \"\\n\")\n\nn_compare_spec &lt;- pwr.2p.test(h = h_spec, n = NULL, sig.level = 0.05, power = 0.80, alternative = \"two.sided\")\n\nprint(n_compare_spec)<\/code><\/pre>\n\n\n\n<p>\u52b9\u679c\u91cf\u306f\u3001\u7d04 -0.404 \u3068\u8a08\u7b97\u3055\u308c\u3001\u5fc5\u8981\u306a\u30b5\u30f3\u30d7\u30eb\u6570\u306f\u300197 \u4eba\u3068\u8a08\u7b97\u3055\u308c\u308b\u3002<\/p>\n\n\n\n<pre class=\"wp-block-code\"><code>> cat(\"\u8a08\u7b97\u3055\u308c\u305f\u52b9\u679c\u91cf (Effect size, h):\", h_spec, \"\\n\")\n\u8a08\u7b97\u3055\u308c\u305f\u52b9\u679c\u91cf (Effect size, h): -0.4036964 \n\n> print(n_compare_spec)\n\n     Difference of proportion power calculation for binomial distribution (arcsine transformation) \n\n              h = 0.4036964\n              n = 96.32225\n      sig.level = 0.05\n          power = 0.8\n    alternative = two.sided\n\nNOTE: same sample sizes<\/code><\/pre>\n\n\n\n<h2 class=\"wp-block-heading\">\u7d50\u679c\u306e\u89e3\u91c8\u3068\u7dcf\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba<\/h2>\n\n\n\n<p>pwr.2p.test \u306e\u51fa\u529b\u306b\u542b\u307e\u308c\u308b n \u306f\u3001\u5404\u7fa4\u306b\u5fc5\u8981\u306a\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3092\u793a\u3057\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p>\u611f\u5ea6\u6bd4\u8f03\u306e\u5834\u5408: \u7b97\u51fa\u3055\u308c\u305f n \u306f\u3001\u75be\u60a3\u306e\u3042\u308b\u88ab\u9a13\u8005\u306e\u5404\u7fa4\u306b\u304a\u3051\u308b\u5fc5\u8981\u306a\u6570\u3067\u3042\u308b\u3002\u4f8b\u3048\u3070\u3001\u4e0a\u8a18\u306e\u3088\u3046\u306b n = 119 \u3068\u51fa\u305f\u3089\u3001\u691c\u67fbA\u306e\u611f\u5ea6\u8a55\u4fa1\u306b119\u4eba\u306e\u75be\u60a3\u3042\u308a\u88ab\u9a13\u8005\u3001\u691c\u67fbB\u306e\u611f\u5ea6\u8a55\u4fa1\u306b119\u4eba\u306e\u75be\u60a3\u3042\u308a\u88ab\u9a13\u8005\u3001\u5408\u8a08238\u4eba\u306e\u75be\u60a3\u3042\u308a\u88ab\u9a13\u8005\u304c\u5fc5\u8981\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308b\u3002<\/p>\n\n\n\n<p>\u7279\u7570\u5ea6\u6bd4\u8f03\u306e\u5834\u5408: \u7b97\u51fa\u3055\u308c\u305f n \u306f\u3001\u75be\u60a3\u306e\u306a\u3044\u88ab\u9a13\u8005\u306e\u5404\u7fa4\u306b\u304a\u3051\u308b\u5fc5\u8981\u306a\u6570\u3067\u3042\u308b\u3002<\/p>\n\n\n\n<p>\u4e21\u65b9\u306e\u6bd4\u8f03\u3092\u8003\u616e\u3059\u308b\u5834\u5408\u3001\u611f\u5ea6\u3068\u7279\u7570\u5ea6\u305d\u308c\u305e\u308c\u3067\u5fc5\u8981\u306a\u300c\u75be\u60a3\u3042\u308a\u300d\u3068\u300c\u75be\u60a3\u306a\u3057\u300d\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3092\u8a08\u7b97\u3057\u3001\u6709\u75c5\u7387\u3092\u8003\u616e\u3057\u3066\u6700\u7d42\u7684\u306a\u7dcf\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3092\u6c7a\u5b9a\u3059\u308b\u3053\u3068\u306b\u306a\u308b\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u611f\u5ea6\u6bd4\u8f03\u3067\u75be\u60a3\u3042\u308a\u88ab\u9a13\u8005\u304c\u5404\u7fa4119\u4eba\u3001\u7279\u7570\u5ea6\u6bd4\u8f03\u3067\u75be\u60a3\u306a\u3057\u88ab\u9a13\u8005\u304c\u5404\u7fa497\u4eba\u5fc5\u8981\u306b\u306a\u3063\u305f\u3068\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6709\u75c5\u7387\u304c20%\u306e\u5834\u5408\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u75be\u60a3\u3042\u308a\u88ab\u9a13\u8005\u306e\u78ba\u4fdd\u306b\u5fc5\u8981\u306a\u7dcf\u60a3\u8005\u6570: (119 + 119) \/ 0.20 = 238 \/ 0.20 =  1190 \u4eba<\/li>\n\n\n\n<li>\u75be\u60a3\u306a\u3057\u88ab\u9a13\u8005\u306e\u78ba\u4fdd\u306b\u5fc5\u8981\u306a\u7dcf\u60a3\u8005\u6570: (97 + 97) \/ (1 &#8211; 0.20) = 194 \/ 0.80 = 243 \u4eba<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u5834\u5408\u3001\u611f\u5ea6\u6bd4\u8f03\u306e\u6761\u4ef6\u3092\u6e80\u305f\u3059\u305f\u3081\u306b\u7dcf\u8a081190\u4eba\u306e\u60a3\u8005\u304c\u5fc5\u8981\u3068\u306a\u308b\u3002\u3053\u306e1190\u4eba\u306e\u4e2d\u306b\u306f\u3001238\u4eba\u306e\u75be\u60a3\u3042\u308a\u60a3\u8005\u3068952\u4eba\u306e\u75be\u60a3\u306a\u3057\u60a3\u8005\u304c\u542b\u307e\u308c\u308b\u3053\u3068\u306b\u306a\u308b\u3002\u7279\u7570\u5ea6\u8a55\u4fa1\u306b\u5fc5\u8981\u306a243\u4eba\u306e\u75be\u60a3\u306a\u3057\u60a3\u8005\u306f\u3001\u3053\u306e952\u4eba\u306e\u4e2d\u306b\u542b\u307e\u308c\u308b\u305f\u3081\u3001\u5168\u4f53\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u306f1190\u4eba\u3068\u306a\u308b\u3002<\/p>\n\n\n\n<p><strong>\u6ce8\u610f\u4e8b\u9805:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u52b9\u679c\u91cf h \u306f\u30012\u3064\u306e\u5272\u5408\u306e\u5dee\u304c\u5c0f\u3055\u3044\u307b\u3069\uff08\u3064\u307e\u308a\u3001\u691c\u51fa\u3057\u305f\u3044\u5dee\u304c\u5c0f\u3055\u3044\u307b\u3069\uff09\u3001\u5927\u304d\u306a\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u304c\u5fc5\u8981\u306b\u306a\u308b\u3002<\/li>\n\n\n\n<li>\u81e8\u5e8a\u7684\u306b\u610f\u5473\u306e\u3042\u308b\u6700\u5c0f\u306e\u5dee\uff08Minimum Clinically Important Difference, MCID\uff09\u3092\u8003\u616e\u3057\u3066\u3001\u52b9\u679c\u91cf\u3092\u8a2d\u5b9a\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3002<\/li>\n\n\n\n<li>\u3053\u308c\u306f\u30012\u3064\u306e\u72ec\u7acb\u3057\u305f\u7fa4\u3067\u306e\u6bd4\u7387\u306e\u5dee\u3092\u691c\u5b9a\u3059\u308b\u4e00\u822c\u7684\u306a\u65b9\u6cd5\u3067\u3042\u308b\u3002\u8a3a\u65ad\u691c\u67fb\u306e\u6bd4\u8f03\u3067\u306f\u3001\u540c\u3058\u60a3\u8005\u7fa4\u30672\u3064\u306e\u691c\u67fb\u3092\u884c\u3046\u5bfe\u5fdc\u306e\u3042\u308b\u30c7\u30fc\u30bf\u3068\u306a\u308b\u3053\u3068\u304c\u591a\u3044\u3002\u5bfe\u5fdc\u306e\u3042\u308b\u30c7\u30fc\u30bf\u306e\u6bd4\u7387\u306e\u6bd4\u8f03\u306b\u306f\u3001\u30de\u30af\u30cd\u30de\u30fc\u691c\u5b9a\u306b\u57fa\u3065\u3044\u305f\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u8a08\u7b97\u304c\u5fc5\u8981\u3067\u3001\u4e0a\u8a18\u306e pwr.2p.test \u306f\u76f4\u63a5\u9069\u7528\u3067\u304d\u306a\u3044\u3002\u30de\u30af\u30cd\u30de\u30fc\u691c\u5b9a\u306b\u57fa\u3065\u304f\u5fc5\u8981\u306a\u30b5\u30f3\u30d7\u30eb\u6570\u8a08\u7b97\u306f\u4ee5\u4e0b\u306e\u95a2\u9023\u8a18\u4e8b\u3092\u53c2\u7167\u306e\u3053\u3068\u3002<\/li>\n<\/ul>\n\n\n<div class=\"swell-block-postLink\">\t\t\t<div class=\"p-blogCard -internal\" data-type=\"type1\" data-onclick=\"clickLink\">\n\t\t\t\t<div class=\"p-blogCard__inner\">\n\t\t\t\t\t<span class=\"p-blogCard__caption\">\u3042\u308f\u305b\u3066\u8aad\u307f\u305f\u3044<\/span>\n\t\t\t\t\t<div class=\"p-blogCard__thumb c-postThumb\"><figure class=\"c-postThumb__figure\"><img decoding=\"async\" src=\"https:\/\/best-biostatistics.com\/toukei-er\/wp-content\/uploads\/2024\/08\/1920x1080-video-Excel-300x169.jpg\" alt=\"\" class=\"c-postThumb__img u-obf-cover\" width=\"320\" height=\"180\"><\/figure><\/div>\t\t\t\t\t<div class=\"p-blogCard__body\">\n\t\t\t\t\t\t<a class=\"p-blogCard__title\" href=\"https:\/\/best-biostatistics.com\/toukei-er\/entry\/r-script-for-mcnemar-test-sample-size-calculation\/\">R \u3067\u30de\u30af\u30cd\u30de\u30fc\u691c\u5b9a\u306b\u5fc5\u8981\u306a\u30b5\u30f3\u30d7\u30eb\u6570\u3092\u8a08\u7b97\u3059\u308b\u65b9\u6cd5<\/a>\n\t\t\t\t\t\t<span class=\"p-blogCard__excerpt\">\u300c\u6cbb\u7642\u524d\u5f8c\u306e\u52b9\u679c\u300d\u300c\u65bd\u7b56\u306b\u3088\u308b\u610f\u8b58\u306e\u5909\u5316\u300d\u306a\u3069\u3001\u540c\u3058\u5bfe\u8c61\u8005\u306e2\u3064\u306e\u6642\u70b9\u3067\u306e\u5909\u5316\u3092\u77e5\u308a\u305f\u3044\u3068\u304d\u3001\u30de\u30af\u30cd\u30de\u30fc\u691c\u5b9a\u304c\u5f79\u7acb\u3064\u3002\u3053\u306e\u691c\u5b9a\u306f2\u5024\u30c7\u30fc\u30bf\uff08\u306f\u3044\/\u3044\u3044\u3048\u306a\u3069\uff09\u306e&#8230;<\/span>\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\n\n<h2 class=\"wp-block-heading\">\u307e\u3068\u3081<\/h2>\n\n\n\n<p>\u8a3a\u65ad\u691c\u67fb\u306e\u611f\u5ea6\u30fb\u7279\u7570\u5ea6\u5206\u6790\u306b\u304a\u3051\u308b\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u8a08\u7b97\u306f\u3001\u7814\u7a76\u306e\u4fe1\u983c\u6027\u3068\u52b9\u7387\u3092\u5de6\u53f3\u3059\u308b\u8981\u3067\u3042\u308b\u3002\u5358\u4e00\u306e\u611f\u5ea6\u3084\u7279\u7570\u5ea6\u3092\u6b63\u78ba\u306b\u63a8\u5b9a\u3059\u308b\u5834\u5408\u3082\u3001\u8907\u6570\u306e\u691c\u67fb\u3092\u6bd4\u8f03\u3059\u308b\u5834\u5408\u3082\u3001\u671f\u5f85\u5024\u3001\u6709\u75c5\u7387\u3001\u8a31\u5bb9\u8aa4\u5dee\u3001\u691c\u51fa\u529b\u3068\u3044\u3063\u305f\u8981\u7d20\u3092\u614e\u91cd\u306b\u8003\u616e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002\u9069\u5207\u306a\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u8a2d\u5b9a\u306f\u3001\u8cbb\u7528\u5bfe\u52b9\u679c\u306e\u9ad8\u3044\u3001\u502b\u7406\u7684\u304b\u3064\u7d71\u8a08\u7684\u306b\u610f\u7fa9\u306e\u3042\u308b\u7814\u7a76\u3092\u5b9f\u65bd\u3059\u308b\u305f\u3081\u306b\u4e0d\u53ef\u6b20\u3002\u672c\u8a18\u4e8b\u304c\u3001\u3042\u306a\u305f\u306e\u7814\u7a76\u8a08\u753b\u306e\u4e00\u52a9\u3068\u306a\u308c\u3070\u5e78\u3044\u3067\u3042\u308b\u3002<\/p>\n\n\n\n\n","protected":false},"excerpt":{"rendered":"<p>\u8a3a\u65ad\u691c\u67fb\u306e\u611f\u5ea6\u30fb\u7279\u7570\u5ea6\u5206\u6790\u306b\u304a\u3051\u308b\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u8a08\u7b97\u306f\u3001\u7814\u7a76\u306e\u76ee\u7684\u3001\u75be\u60a3\u6709\u75c5\u7387\u3001\u671f\u5f85\u3055\u308c\u308b\u611f\u5ea6\u30fb\u7279\u7570\u5ea6\u3001\u8a31\u5bb9\u8aa4\u5dee\u3001\u691c\u51fa\u529b\u306b\u57fa\u3065\u3044\u3066\u884c\u308f\u308c\u308b\u3002\u5c0f\u3055\u3059\u304e\u308b\u3068\u4fe1\u983c\u6027\u304c\u4f4e\u304f\u3001\u5927\u304d\u3059\u304e\u308b\u3068\u30ea\u30bd\u30fc\u30b9\u304c\u7121\u99c4\u306b\u306a\u308b\u3002\u7d71\u8a08\u7684\u306b\u4fe1\u983c\u3067\u304d\u308b\u7d50 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"swell_btn_cv_data":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[5,16,141],"tags":[],"class_list":["post-3132","post","type-post","status-publish","format-standard","hentry","category-r","category-16","category-141"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/posts\/3132","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/comments?post=3132"}],"version-history":[{"count":14,"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/posts\/3132\/revisions"}],"predecessor-version":[{"id":3966,"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/posts\/3132\/revisions\/3966"}],"wp:attachment":[{"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/media?parent=3132"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/categories?post=3132"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/tags?post=3132"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}