{"id":4031,"date":"2025-06-17T21:41:53","date_gmt":"2025-06-17T12:41:53","guid":{"rendered":"https:\/\/best-biostatistics.com\/toukei-er\/?p=4031"},"modified":"2025-06-17T21:41:55","modified_gmt":"2025-06-17T12:41:55","slug":"biological-equivalence-study-ninety-percent-confidence-intervals-importance","status":"publish","type":"post","link":"https:\/\/best-biostatistics.com\/toukei-er\/entry\/biological-equivalence-study-ninety-percent-confidence-intervals-importance\/","title":{"rendered":"\u751f\u7269\u5b66\u7684\u540c\u7b49\u6027\u8a66\u9a13\u306b\u304a\u3051\u308b90\uff05\u4fe1\u983c\u533a\u9593\u306e\u91cd\u8981\u6027"},"content":{"rendered":"\n<p>\u65b0\u85ac\u958b\u767a\u3084\u5f8c\u767a\u533b\u85ac\u54c1\uff08\u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u533b\u85ac\u54c1\uff09\u306e\u958b\u767a\u306b\u304a\u3044\u3066\u3001\u85ac\u5264\u306e\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027\u3092\u79d1\u5b66\u7684\u306b\u8a55\u4fa1\u3059\u308b\u3053\u3068\u306f\u6975\u3081\u3066\u91cd\u8981\u3067\u3042\u308b\u3002\u305d\u306e\u4e2d\u3067\u3082\u3001\u3059\u3067\u306b\u627f\u8a8d\u3055\u308c\u3066\u3044\u308b\u533b\u85ac\u54c1\uff08\u5148\u767a\u533b\u85ac\u54c1\uff09\u3068\u65b0\u3057\u3044\u533b\u85ac\u54c1\u304c\u3001\u4f53\u5185\u3067\u540c\u7b49\u306b\u4f5c\u7528\u3059\u308b\u304b\u3092\u8a55\u4fa1\u3059\u308b<strong>\u751f\u7269\u5b66\u7684\u540c\u7b49\u6027\u8a66\u9a13<\/strong>\u306f\u3001\u975e\u5e38\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u308b\u3002\u3053\u306e\u8a66\u9a13\u3067\u306f\u3001\u4e00\u822c\u7684\u306a\u7d71\u8a08\u5b66\u7684\u6709\u610f\u6027\u691c\u5b9a\u3067\u7528\u3044\u3089\u308c\u308b95%\u4fe1\u983c\u533a\u9593\u3067\u306f\u306a\u304f\u3001<strong>90%\u4fe1\u983c\u533a\u9593<\/strong>\u304c\u4f7f\u7528\u3055\u308c\u308b\u3002\u306a\u305c90%\u4fe1\u983c\u533a\u9593\u304c\u63a1\u7528\u3055\u308c\u308b\u306e\u304b\u3001\u305d\u306e\u7406\u7531\u3068\u3001\u7d71\u8a08\u5b66\u7684\u6709\u610f\u6027\u3068\u306e\u9055\u3044\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac\u3059\u308b\u3002<\/p>\n\n\n\n<!--more-->\n\n\n\n<h2 class=\"wp-block-heading\">\u751f\u7269\u5b66\u7684\u540c\u7b49\u6027\u8a66\u9a13\u306e\u6982\u8981<\/h2>\n\n\n\n<p>\u751f\u7269\u5b66\u7684\u540c\u7b49\u6027\u8a66\u9a13\u306f\u3001\u4e3b\u306b\u5f8c\u767a\u533b\u85ac\u54c1\u304c\u5148\u767a\u533b\u85ac\u54c1\u3068\u300c\u751f\u7269\u5b66\u7684\u306b\u540c\u7b49\u3067\u3042\u308b\u300d\u3053\u3068\u3092\u8a3c\u660e\u3059\u308b\u305f\u3081\u306b\u884c\u308f\u308c\u308b\u81e8\u5e8a\u8a66\u9a13\u3067\u3042\u308b\u3002\u5177\u4f53\u7684\u306b\u306f\u3001\u540c\u3058\u6709\u52b9\u6210\u5206\u3092\u542b\u6709\u3059\u308b2\u3064\u306e\u85ac\u5264\uff08\u8a66\u9a13\u85ac\u3068\u5bfe\u7167\u85ac\uff09\u3092\u5065\u5eb7\u306a\u88ab\u9a13\u8005\u306b\u6295\u4e0e\u3057\u3001\u8840\u4e2d\u6fc3\u5ea6\u63a8\u79fb\u3092\u6e2c\u5b9a\u3059\u308b\u3002\u305d\u3057\u3066\u3001\u8840\u4e2d\u6fc3\u5ea6\u66f2\u7dda\u4e0b\u9762\u7a4d\uff08AUC\uff09\u3084\u6700\u9ad8\u8840\u4e2d\u6fc3\u5ea6\uff08Cmax\uff09\u3068\u3044\u3063\u305f\u85ac\u7269\u52d5\u614b\u30d1\u30e9\u30e1\u30fc\u30bf\u3092\u6bd4\u8f03\u3057\u3001\u4e21\u85ac\u5264\u306e\u5438\u53ce\u901f\u5ea6\u3068\u5438\u53ce\u91cf\u304c\u540c\u7b49\u3067\u3042\u308b\u3053\u3068\u3092\u7d71\u8a08\u5b66\u7684\u306b\u8a55\u4fa1\u3059\u308b\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u52b9\u679c\u3068\u5b89\u5168\u6027\u304c\u5148\u767a\u533b\u85ac\u54c1\u3068\u540c\u7b49\u3067\u3042\u308b\u3068\u5224\u65ad\u3055\u308c\u3001\u5f8c\u767a\u533b\u85ac\u54c1\u306e\u627f\u8a8d\u3078\u3068\u7e4b\u304c\u308b\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">90\uff05\u4fe1\u983c\u533a\u9593\u304c\u7528\u3044\u3089\u308c\u308b\u7406\u7531<\/h2>\n\n\n\n<p>\u751f\u7269\u5b66\u7684\u540c\u7b49\u6027\u8a66\u9a13\u306790%\u4fe1\u983c\u533a\u9593\u304c\u7528\u3044\u3089\u308c\u308b\u4e3b\u306a\u7406\u7531\u306f\u3001<strong>\u53cc\u65b9\u5411\u6027\u306e\u540c\u7b49\u6027\uff08two-sided equivalence\uff09<\/strong>\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u3067\u3042\u308b\u3002\u901a\u5e38\u306e\u7d71\u8a08\u5b66\u7684\u6709\u610f\u6027\u691c\u5b9a\u3067\u306f\u3001\u300c\u5dee\u304c\u3042\u308b\u304b\u306a\u3044\u304b\u300d\u300c\u52b9\u679c\u304c\u3042\u308b\u304b\u3069\u3046\u304b\u300d\u3068\u3044\u3046\u4eee\u8aac\uff08\u4f8b\uff1a\u85acA\u306f\u85acB\u3088\u308a\u3082\u52b9\u679c\u304c\u3042\u308b\uff09\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306b\u4e21\u5074\u691c\u5b9a \u3042\u308b\u3044\u306f \u4e21\u5074 2.5 %\u305a\u3064\u68c4\u5374\u57df\u3092\u8a2d\u3051\u305f\u300195%\u4fe1\u983c\u533a\u9593\u304c\u7528\u3044\u3089\u308c\u308b\u3002\u3057\u304b\u3057\u3001\u751f\u7269\u5b66\u7684\u540c\u7b49\u6027\u8a66\u9a13\u3067\u306f\u3001<strong>\u8a66\u9a13\u85ac\u304c\u5bfe\u7167\u85ac\u3088\u308a\u512a\u308c\u3066\u3044\u3066\u3082\u52a3\u3063\u3066\u3044\u3066\u3082\u3044\u3051\u306a\u304f\u3001<\/strong>\u4e21\u8005\u304c\u300c\u5341\u5206\u306b\u540c\u7b49\u3067\u3042\u308b\u300d\u3053\u3068\u3092\u793a\u3059\u5fc5\u8981\u304c\u3042\u308b\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u300c\u5341\u5206\u306b\u540c\u7b49\u3067\u3042\u308b\u300d\u3053\u3068\u3092\u7d71\u8a08\u7684\u306b\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306b\u3001\u8a2d\u5b9a\u3055\u308c\u305f\u540c\u7b49\u6027\u8a31\u5bb9\u57df\uff08\u901a\u5e38\u3001\u5e73\u5747\u5024\u306e\u6bd4\u304c0.80\uff5e1.25\u306e\u7bc4\u56f2\uff09\u306e\u4e2d\u306b\u3001\u85ac\u7269\u52d5\u614b\u30d1\u30e9\u30e1\u30fc\u30bf\u306e\u5e7e\u4f55\u5e73\u5747\u5024\u306e\u6bd4\u306e90%\u4fe1\u983c\u533a\u9593\u5168\u4f53\u304c\u53ce\u307e\u3063\u3066\u3044\u308b\u304b\u3069\u3046\u304b\u3092\u78ba\u8a8d\u3059\u308b\u3002\u3053\u308c\u306f\u3001\u5b9f\u8cea\u7684\u306b\u4ee5\u4e0b\u306e2\u3064\u306e\u7247\u5074\u691c\u5b9a\u3092\u540c\u6642\u306b\u884c\u3063\u3066\u3044\u308b\u3053\u3068\u306b\u76f8\u5f53\u3059\u308b\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>\u8a66\u9a13\u85ac\u306e\u85ac\u7269\u52d5\u614b\u30d1\u30e9\u30e1\u30fc\u30bf\u304c\u3001\u5bfe\u7167\u85ac\u3088\u308a\u3082<strong>\u904e\u5ea6\u306b\u5927\u304d\u304f\u306a\u3044<\/strong>\u3053\u3068\uff08\u4e0a\u9650\u3092\u8d85\u3048\u306a\u3044\u3053\u3068\uff09 <\/li>\n\n\n\n<li>\u8a66\u9a13\u85ac\u306e\u85ac\u7269\u52d5\u614b\u30d1\u30e9\u30e1\u30fc\u30bf\u304c\u3001\u5bfe\u7167\u85ac\u3088\u308a\u3082<strong>\u904e\u5ea6\u306b\u5c0f\u3055\u304f\u306a\u3044<\/strong>\u3053\u3068\uff08\u4e0b\u9650\u3092\u4e0b\u56de\u3089\u306a\u3044\u3053\u3068\uff09<\/li>\n<\/ol>\n\n\n\n<p>\u305d\u308c\u305e\u308c\u306e\u7247\u5074\u691c\u5b9a\u30675%\u306e\u6709\u610f\u6c34\u6e96\u3092\u8a2d\u5b9a\u3059\u308b\u3068\u3001\u4e21\u5074\u3067\u5408\u8a0810%\u306e\u30ea\u30b9\u30af\uff08\u3064\u307e\u308a\u3001\u8aa4\u3063\u3066\u540c\u7b49\u3068\u5224\u65ad\u3057\u3066\u3057\u307e\u3046\u30ea\u30b9\u30af\uff09\u3092\u8a31\u5bb9\u3059\u308b\u3053\u3068\u306b\u306a\u308b\u3002\u3064\u307e\u308a\u3001\u3053\u308c\u304c 90%\u4fe1\u983c\u533a\u9593\u3068\u3044\u3046\u3053\u3068\u3067\u3042\u308b\u3002\u3082\u305795%\u4fe1\u983c\u533a\u9593\u3092\u7528\u3044\u3066\u3057\u307e\u3046\u3068\u3001\u4e21\u5074\u306e\u4fe1\u983c\u533a\u9593\u304c\u305d\u308c\u305e\u308c2.5%\u305a\u3064\u306e\u6709\u610f\u6c34\u6e96\u3067\u8a08\u7b97\u3055\u308c\u3001\u540c\u7b49\u6027\u3092\u793a\u3059\u305f\u3081\u306e\u57fa\u6e96\u304c\u53b3\u3057\u3059\u304e\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/p>\n\n\n\n<div id=\"biost-1522710993\" class=\"biost- biost-entity-placement\"><p style=\"text-align: center;\"><span style=\"font-size: 20px;\"><strong><a href=\"https:\/\/best-biostatistics.com\/kmhl\">\uff1e\uff1e\u3082\u3046\u7d71\u8a08\u3067\u60a9\u3080\u306e\u306f\u7d42\u308f\u308a\u306b\u3057\u307e\u305b\u3093\u304b\uff1f\u00a0<\/a><\/strong><\/span><\/p>\r\n<a href=\"https:\/\/best-biostatistics.com\/kmhl\"><img class=\"aligncenter wp-image-2794 size-full\" 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class=\"has-fixed-layout\"><tbody><tr><td>\u7279\u5fb4<\/td><td>\u751f\u7269\u5b66\u7684\u540c\u7b49\u6027\u8a66\u9a13<\/td><td>\u7d71\u8a08\u5b66\u7684\u6709\u610f\u6027\u8a66\u9a13<\/td><\/tr><tr><td>\u76ee\u7684<\/td><td>\u4e21\u85ac\u5264\u304c\u540c\u7b49\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3059<\/td><td>\u8a66\u9a13\u7fa4\u3068\u5bfe\u7167\u7fa4\u306b\u5dee\u304c\u3042\u308b\u3053\u3068\u3092\u793a\u3059<\/td><\/tr><tr><td>\u4fe1\u983c\u533a\u9593\u306e\u8a2d\u5b9a<\/td><td>90%\u4fe1\u983c\u533a\u9593<\/td><td>95%\u4fe1\u983c\u533a\u9593<\/td><\/tr><tr><td>\u691c\u5b9a\u306e\u65b9\u5411\u6027<\/td><td>\u53cc\u65b9\u5411\u6027\u306e\u540c\u7b49\u6027\uff08\u8a66\u9a13\u85ac\u304c\u5bfe\u7167\u85ac\u3088\u308a\u512a\u308c\u3066\u3082\u52a3\u3063\u3066\u3082\u3044\u3051\u306a\u3044\uff09<\/td><td>\u4e21\u5074\u691c\u5b9a\uff08\u5dee\u306e\u6709\u7121\uff09<\/td><\/tr><tr><td>\u5e30\u7121\u4eee\u8aac<\/td><td>2\u3064\u306e\u85ac\u5264\u304c\u540c\u7b49\u3067\u306f\u306a\u3044\uff08\u5dee\u304c\u3042\u308b\uff09<\/td><td>2\u3064\u306e\u85ac\u5264\u306b\u5dee\u304c\u306a\u3044<\/td><\/tr><tr><td>\u5bfe\u7acb\u4eee\u8aac<\/td><td>2\u3064\u306e\u85ac\u5264\u304c\u540c\u7b49\u3067\u3042\u308b<\/td><td>2\u3064\u306e\u85ac\u5264\u306b\u5dee\u304c\u3042\u308b<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u7d71\u8a08\u5b66\u7684\u6709\u610f\u6027\u8a66\u9a13\u3067\u306f\u3001\u4e3b\u306b\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u304c\u65e2\u5b58\u306e\u6cbb\u7642\u6cd5\u3084\u30d7\u30e9\u30bb\u30dc\u3088\u308a\u3082\u52b9\u679c\u304c\u3042\u308b\u304b\u3001\u3042\u308b\u3044\u306f\u3042\u308b\u4ecb\u5165\u304c\u7279\u5b9a\u306e\u52b9\u679c\u3092\u3082\u305f\u3089\u3059\u304b\u3092\u691c\u8a3c\u3059\u308b\u3002\u3053\u3053\u3067\u306f\u3001\u300c\u52b9\u679c\u304c\u306a\u3044\u300d\u3068\u3044\u3046\u5e30\u7121\u4eee\u8aac\u3092\u68c4\u5374\u3057\u3001\u300c\u52b9\u679c\u304c\u3042\u308b\u300d\u3068\u3044\u3046\u5bfe\u7acb\u4eee\u8aac\u3092\u63a1\u629e\u3059\u308b\u3053\u3068\u304c\u76ee\u7684\u3067\u3042\u308b\u3002\u3053\u306e\u969b\u3001\u7b2c1\u7a2e\u306e\u904e\u8aa4\uff08\u8aa4\u3063\u3066\u52b9\u679c\u304c\u3042\u308b\u3068\u5224\u65ad\u3057\u3066\u3057\u307e\u3046\u30ea\u30b9\u30af\uff09\u30925%\u4ee5\u4e0b\u306b\u6291\u3048\u308b\u305f\u3081\u306b\u3001\u4e00\u822c\u7684\u306b95%\u4fe1\u983c\u533a\u9593\u304c\u7528\u3044\u3089\u308c\u308b\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3001\u751f\u7269\u5b66\u7684\u540c\u7b49\u6027\u8a66\u9a13\u3067\u306f\u3001<strong>\u5e30\u7121\u4eee\u8aac\u306f\u300c2\u3064\u306e\u85ac\u5264\u306f\u540c\u7b49\u3067\u306f\u306a\u3044\uff08\u5dee\u304c\u3042\u308b\uff09\u300d<\/strong>\u3067\u3042\u308a\u3001<strong>\u5bfe\u7acb\u4eee\u8aac\u306f\u300c2\u3064\u306e\u85ac\u5264\u306f\u540c\u7b49\u3067\u3042\u308b\u300d<\/strong>\u3068\u306a\u308b\u3002\u3064\u307e\u308a\u3001\u901a\u5e38\u306e\u6709\u610f\u6027\u691c\u5b9a\u3068\u306f\u4eee\u8aac\u306e\u7acb\u3066\u65b9\u304c\u9006\u8ee2\u3057\u3066\u3044\u308b\u300290%\u4fe1\u983c\u533a\u9593\u304c\u540c\u7b49\u6027\u8a31\u5bb9\u57df\u5185\u306b\u53ce\u307e\u308b\u3053\u3068\u3067\u3001\u5e30\u7121\u4eee\u8aac\u304c\u68c4\u5374\u3055\u308c\u3001\u4e21\u85ac\u5264\u304c\u751f\u7269\u5b66\u7684\u306b\u540c\u7b49\u3067\u3042\u308b\u3068\u7d50\u8ad6\u3065\u3051\u3089\u308c\u308b\u3002<\/p>\n\n\n\n<h2 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