{"id":4248,"date":"2025-07-15T23:22:12","date_gmt":"2025-07-15T14:22:12","guid":{"rendered":"https:\/\/best-biostatistics.com\/toukei-er\/?p=4248"},"modified":"2025-07-15T23:22:45","modified_gmt":"2025-07-15T14:22:45","slug":"meta-analysis-of-cohort-studies-integrating-adjusted-odds-ratios-and-adjusted-hazard-ratios","status":"publish","type":"post","link":"https:\/\/best-biostatistics.com\/toukei-er\/entry\/meta-analysis-of-cohort-studies-integrating-adjusted-odds-ratios-and-adjusted-hazard-ratios\/","title":{"rendered":"\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306b\u304a\u3051\u308b\u8abf\u6574\u30aa\u30c3\u30ba\u6bd4\u3068\u8abf\u6574\u30cf\u30b6\u30fc\u30c9\u6bd4\u306e\u7d71\u5408"},"content":{"rendered":"\n<p>\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306f\u3001\u8907\u6570\u306e\u72ec\u7acb\u3057\u305f\u7814\u7a76\u7d50\u679c\u3092\u7d71\u5408\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u4fe1\u983c\u6027\u306e\u9ad8\u3044\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u5c0e\u304d\u51fa\u3059\u5f37\u529b\u306a\u624b\u6cd5\u3067\u3042\u308b\u3002\u7279\u306b\u3001<strong>\u8abf\u6574\u30aa\u30c3\u30ba\u6bd4 (Adjusted Odds Ratio: AOR)<\/strong> \u3084 <strong>\u8abf\u6574\u30cf\u30b6\u30fc\u30c9\u6bd4 (Adjusted Hazard Ratio: AHR)<\/strong> \u306e\u3088\u3046\u306a\u3001\u4ea4\u7d61\u56e0\u5b50\u3092\u8abf\u6574\u3057\u305f\u52b9\u679c\u6307\u6a19\u3092\u7d71\u5408\u3059\u308b\u969b\u306b\u306f\u3001\u305d\u306e\u7279\u6027\u3092\u7406\u89e3\u3057\u3001\u9069\u5207\u306a\u65b9\u6cd5\u3067\u89e3\u6790\u3092\u9032\u3081\u308b\u3053\u3068\u304c\u4e0d\u53ef\u6b20\u3067\u3042\u308b\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306b\u304a\u3044\u3066\u3001AOR\u3084AHR\u3092\u7d71\u5408\u3059\u308b\u969b\u306e\u4e00\u9023\u306e\u624b\u9806\u3092\u3001\u30c7\u30fc\u30bf\u306e\u6e96\u5099\u304b\u3089R\u3092\u7528\u3044\u305f\u8a08\u7b97\u4f8b\u307e\u3067\u3001\u5177\u4f53\u7684\u306b\u89e3\u8aac\u3059\u308b\u3002<\/p>\n\n\n\n<!--more-->\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u30c7\u30fc\u30bf\u306e\u6e96\u5099\u65b9\u6cd5<\/h2>\n\n\n\n<p>\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3092\u884c\u3046\u306b\u306f\u3001\u307e\u305a\u5404\u7814\u7a76\u304b\u3089\u5fc5\u8981\u306a\u30c7\u30fc\u30bf\u3092\u62bd\u51fa\u3057\u3066\u6574\u7406\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002AOR\u3084AHR\u3092\u7d71\u5408\u3059\u308b\u5834\u5408\u3001\u4ee5\u4e0b\u306e\u60c5\u5831\u304c\u5404\u7814\u7a76\u304b\u3089\u62bd\u51fa\u3055\u308c\u3066\u3044\u308b\u304b\u3092\u78ba\u8a8d\u3055\u308c\u305f\u3044\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u8abf\u6574\u30aa\u30c3\u30ba\u6bd4 (AOR) \u307e\u305f\u306f\u8abf\u6574\u30cf\u30b6\u30fc\u30c9\u6bd4 (AHR)<\/strong>: \u5404\u7814\u7a76\u3067\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u5024\u3002<\/li>\n\n\n\n<li><strong>95%\u4fe1\u983c\u533a\u9593 (95% CI) \u307e\u305f\u306f\u6a19\u6e96\u8aa4\u5dee (Standard Error: SE)<\/strong>: AOR\u307e\u305f\u306fAHR\u306b\u5bfe\u5fdc\u3059\u308b\u4fe1\u983c\u533a\u9593\u3001\u3082\u3057\u304f\u306f\u76f4\u63a5SE\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u5834\u5408\u3002SE\u304c\u76f4\u63a5\u5831\u544a\u3055\u308c\u3066\u3044\u306a\u3044\u5834\u5408\u306f\u3001\u4fe1\u983c\u533a\u9593\u304b\u3089\u8a08\u7b97\u304c\u53ef\u80fd\u3067\u3042\u308b\u3002<\/li>\n\n\n\n<li><strong>\u7814\u7a76ID\/\u540d\u79f0<\/strong>: \u5404\u7814\u7a76\u3092\u8b58\u5225\u3059\u308b\u305f\u3081\u306e\u56fa\u6709\u306eID\u3084\u540d\u79f0\u3002<\/li>\n\n\n\n<li><strong>\u8457\u8005\u540d\u3001\u51fa\u7248\u5e74\u306a\u3069<\/strong>: \u7814\u7a76\u306e\u7279\u5b9a\u306b\u5f79\u7acb\u3064\u60c5\u5831\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u30c7\u30fc\u30bf\u306f\u3001\u901a\u5e38\u30b9\u30d7\u30ec\u30c3\u30c9\u30b7\u30fc\u30c8\u5f62\u5f0f\uff08\u4f8b: CSV\u3001Excel\uff09\u3067\u6574\u7406\u3059\u308b\u3068\u7ba1\u7406\u3057\u3084\u3059\u304f\u306a\u308b\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u6a19\u6e96\u8aa4\u5dee\u306e\u8a08\u7b97\u65b9\u6cd5<\/h2>\n\n\n\n<p>\u591a\u304f\u306e\u7814\u7a76\u3067\u306f\u3001AOR\u3084AHR\u81ea\u4f53\u306f\u5831\u544a\u3055\u308c\u3066\u3082\u3001\u305d\u306e\u6a19\u6e96\u8aa4\u5dee\u306f\u76f4\u63a5\u5831\u544a\u3055\u308c\u306a\u3044\u3053\u3068\u304c\u3042\u308b\u3002\u305d\u306e\u5834\u5408\u300195%\u4fe1\u983c\u533a\u9593\u304b\u3089\u6a19\u6e96\u8aa4\u5dee\u3092\u9006\u7b97\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002AOR\u3084AHR\u306f\u5bfe\u6570\u5909\u63db\u3059\u308b\u3053\u3068\u3067\u6b63\u898f\u5206\u5e03\u306b\u8fd1\u4f3c\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u305f\u3081\u3001\u5bfe\u6570\u5909\u63db\u5f8c\u306e\u5024\u3068\u305d\u306e\u6a19\u6e96\u8aa4\u5dee\u3092\u4f7f\u7528\u3059\u308b\u3002<\/p>\n\n\n\n<p>AOR\u307e\u305f\u306fAHR\u306e95%\u4fe1\u983c\u533a\u9593\u304c [L,U] \u3067\u4e0e\u3048\u3089\u308c\u3066\u3044\u308b\u5834\u5408\u3001\u5bfe\u6570\u5909\u63db\u5f8c\u306e\u6a19\u6e96\u8aa4\u5dee $ \\text{SE}_{\\text{log(OR or HR)}} $ \u306f\u4ee5\u4e0b\u306e\u5f0f\u3067\u8a08\u7b97\u3067\u304d\u308b\u3002<\/p>\n\n\n\n<p>$$ \\text{SE}_{\\text{log(OR or HR)}} = \\frac{\\log{U} \u2212 \\log{L}}{2\\times 1.96} $$<\/p>\n\n\n\n<p>\u3053\u3053\u3067\u3001log \u306f\u81ea\u7136\u5bfe\u6570\u3092\u8868\u3057\u30011.96 \u306f95%\u4fe1\u983c\u533a\u9593\u306b\u304a\u3051\u308b\u6a19\u6e96\u6b63\u898f\u5206\u5e03\u306eZ\u5024\u3067\u3042\u308b\u3002<\/p>\n\n\n\n<p>\u5404\u7814\u7a76\u304b\u3089\u62bd\u51fa\u3057\u305fAOR\u307e\u305f\u306fAHR\u306e\u5bfe\u6570\u5909\u63db\u5024\u3068\u3001\u4e0a\u8a18\u3067\u7b97\u51fa\u3057\u305f\u5bfe\u6570\u5909\u63db\u5f8c\u306e\u6a19\u6e96\u8aa4\u5dee\u3092\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306b\u7528\u3044\u308b\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<div id=\"biost-1495354828\" class=\"biost- biost-entity-placement\"><p style=\"text-align: center;\"><span style=\"font-size: 20px;\"><strong><a href=\"https:\/\/best-biostatistics.com\/kmhl\">\uff1e\uff1e\u3082\u3046\u7d71\u8a08\u3067\u60a9\u3080\u306e\u306f\u7d42\u308f\u308a\u306b\u3057\u307e\u305b\u3093\u304b\uff1f\u00a0<\/a><\/strong><\/span><\/p>\r\n<a href=\"https:\/\/best-biostatistics.com\/kmhl\"><img class=\"aligncenter wp-image-2794 size-full\" src=\"https:\/\/best-biostatistics.com\/wp\/wp-content\/uploads\/2023\/11\/bn_r_03.png\" alt=\"\" width=\"500\" height=\"327\" \/><\/a>\r\n<p style=\"text-align: center;\"><span style=\"color: #ff0000; font-size: 20px;\"><strong><span class=\"marker2\">\u21911\u4e07\u4eba\u4ee5\u4e0a\u306e\u533b\u7642\u5f93\u4e8b\u8005\u304c\u8cfc\u8aad\u4e2d<\/span><\/strong><\/span><\/p><\/div><h2 class=\"wp-block-heading\">\u7d71\u5408\u65b9\u6cd5<\/h2>\n\n\n\n<p>AOR\u3084AHR\u306e\u7d71\u5408\u306b\u306f\u3001\u4e3b\u306b<strong>\u56fa\u5b9a\u52b9\u679c\u30e2\u30c7\u30eb (Fixed-effect model)<\/strong> \u3068 <strong>\u5909\u91cf\u52b9\u679c\u30e2\u30c7\u30eb (Random-effects model)<\/strong> \u306e2\u3064\u306e\u65b9\u6cd5\u304c\u3042\u308b\u3002\u3069\u3061\u3089\u306e\u30e2\u30c7\u30eb\u3092\u4f7f\u7528\u3059\u308b\u304b\u306f\u3001\u5404\u7814\u7a76\u9593\u306e\u7570\u8cea\u6027\uff08heterogeneity\uff09\u306e\u6709\u7121\u3084\u7a0b\u5ea6\u306b\u3088\u3063\u3066\u6c7a\u5b9a\u3055\u308c\u308b\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u56fa\u5b9a\u52b9\u679c\u30e2\u30c7\u30eb<\/strong>: \u5404\u7814\u7a76\u3067\u89b3\u5bdf\u3055\u308c\u305f\u52b9\u679c\u306f\u3001\u5358\u4e00\u306e\u771f\u306e\u52b9\u679c\u91cf\u306e\u5468\u308a\u306b\u3070\u3089\u3064\u3044\u3066\u3044\u308b\u3068\u4eee\u5b9a\u3059\u308b\u3002\u7814\u7a76\u9593\u306e\u7570\u8cea\u6027\u304c\u4f4e\u3044\u5834\u5408\u306b\u9069\u3057\u3066\u3044\u308b\u3002\u4e00\u822c\u7684\u306b\u3001\u9006\u5206\u6563\u91cd\u307f\u4ed8\u3051\u6cd5\u304c\u7528\u3044\u3089\u308c\u3001\u5404\u7814\u7a76\u306e\u91cd\u307f\u306f\u3001\u305d\u306e\u7814\u7a76\u306e\u7cbe\u5ea6\u306e\u9006\u6570\uff08\u5206\u6563\u306e\u9006\u6570\uff09\u306b\u6bd4\u4f8b\u3059\u308b\u3002<\/li>\n\n\n\n<li><strong>\u5909\u91cf\u52b9\u679c\u30e2\u30c7\u30eb<\/strong>: \u5404\u7814\u7a76\u3067\u89b3\u5bdf\u3055\u308c\u305f\u52b9\u679c\u306f\u3001\u7570\u306a\u308b\u771f\u306e\u52b9\u679c\u91cf\u3092\u6301\u3064\u6bcd\u96c6\u56e3\u304b\u3089\u30e9\u30f3\u30c0\u30e0\u306b\u62bd\u51fa\u3055\u308c\u305f\u3068\u4eee\u5b9a\u3059\u308b\u3002\u7814\u7a76\u9593\u306e\u7570\u8cea\u6027\u304c\u5b58\u5728\u3059\u308b\u3001\u307e\u305f\u306f\u7570\u8cea\u6027\u306e\u5b58\u5728\u304c\u7591\u308f\u308c\u308b\u5834\u5408\u306b\u63a8\u5968\u3055\u308c\u308b\u3002\u3053\u306e\u30e2\u30c7\u30eb\u3067\u306f\u3001\u7814\u7a76\u5185\u5206\u6563\u3060\u3051\u3067\u306a\u304f\u3001\u7814\u7a76\u9593\u5206\u6563\uff08\u7570\u8cea\u6027\u306e\u6307\u6a19\u3067\u3042\u308b$\\tau^2$\uff09\u3082\u91cd\u307f\u306e\u8a08\u7b97\u306b\u8003\u616e\u3055\u308c\u308b\u3002\u591a\u304f\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3067\u306f\u3001\u7570\u8cea\u6027\u304c\u5b8c\u5168\u306b\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u306f\u7a00\u3067\u3042\u308b\u305f\u3081\u3001<strong>\u5909\u91cf\u52b9\u679c\u30e2\u30c7\u30eb\u304c\u63a8\u5968\u3055\u308c\u308b\u3053\u3068\u304c\u591a\u3044<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u30e2\u30c7\u30eb\u3092\u9078\u629e\u3057\u305f\u5f8c\u3001\u7d71\u5408\u3055\u308c\u305f\u52b9\u679c\u91cf\uff08\u7d71\u5408AOR\u307e\u305f\u306f\u7d71\u5408AHR\uff09\u3068\u305d\u306e\u4fe1\u983c\u533a\u9593\u3092\u7b97\u51fa\u3059\u308b\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u5177\u4f53\u4f8b\u3068 R \u8a08\u7b97\u4f8b<\/h2>\n\n\n\n<p>\u3053\u3053\u3067\u306f\u3001R\u306e<code>meta<\/code>\u30d1\u30c3\u30b1\u30fc\u30b8\u3092\u7528\u3044\u305fAOR\u307e\u305f\u306fAHR\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u4f8b\u3092\u793a\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305a\u3001<code>meta<\/code>\u30d1\u30c3\u30b1\u30fc\u30b8\u3092\u30a4\u30f3\u30b9\u30c8\u30fc\u30eb\u3057\u3066\u30ed\u30fc\u30c9\u3059\u308b\u3002<\/p>\n\n\n\n<pre class=\"wp-block-code\"><code># install.packages(\"meta\")\nlibrary(meta)\n<\/code><\/pre>\n\n\n\n<p>\u6b21\u306b\u3001\u67b6\u7a7a\u306e\u30c7\u30fc\u30bf\u30d5\u30ec\u30fc\u30e0\u3092\u4f5c\u6210\u3059\u308b\u3002\u3053\u3053\u3067\u306f\u3001\u5404\u7814\u7a76\u306e\u8abf\u6574\u30aa\u30c3\u30ba\u6bd4\uff08\u307e\u305f\u306f\u8abf\u6574\u30cf\u30b6\u30fc\u30c9\u6bd4\uff09\u3068\u305d\u306e95%\u4fe1\u983c\u533a\u9593\u3092\u4eee\u5b9a\u3059\u308b\u3002<\/p>\n\n\n\n<pre class=\"wp-block-code\"><code># \u67b6\u7a7a\u306e\u30c7\u30fc\u30bf\u4f5c\u6210\ndata_meta &lt;- data.frame(\n  study = c(\"Study A\", \"Study B\", \"Study C\", \"Study D\", \"Study E\"),\n  Ratio = c(1.5, 1.2, 2.1, 1.8, 1.3), # AOR\u307e\u305f\u306fAHR\u306e\u5024\n  lower = c(1.1, 0.9, 1.6, 1.4, 1.0),\n  upper = c(2.0, 1.6, 2.7, 2.3, 1.7)\n)\n<\/code><\/pre>\n\n\n\n<p><code>metagen<\/code>\u95a2\u6570\u3092\u7528\u3044\u3066\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3092\u5b9f\u884c\u3059\u308b\u3002\u3053\u3053\u3067\u306f\u3001<code>TE<\/code>\u306b\u5bfe\u6570\u5909\u63db\u3057\u305fRatio\u3001<code>seTE<\/code>\u306b\u5bfe\u6570\u5909\u63db\u3057\u305fRatio\u306e\u6a19\u6e96\u8aa4\u5dee\u3092\u6307\u5b9a\u3059\u308b\u3002\u307e\u305f\u3001<code>sm=\"OR\"<\/code>\u3084<code>sm=\"HR\"<\/code>\u3067\u52b9\u679c\u6307\u6a19\u306e\u7a2e\u985e\u3092\u6307\u5b9a\u3059\u308b\u3002<\/p>\n\n\n\n<pre class=\"wp-block-code\"><code># \u5909\u91cf\u52b9\u679c\u30e2\u30c7\u30eb\u3092\u7528\u3044\u305f\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\n# Ratio, lower, upper\u3092\u76f4\u63a5\u6307\u5b9a\u3059\u308b\u3053\u3068\u3082\u53ef\u80fd\nmeta_result &lt;- metagen(\n  TE = log(Ratio),\n  lower = log(lower),\n  upper = log(upper),\n  data = data_meta,\n  studlab = study,\n  sm = \"OR\", # \u52b9\u679c\u6307\u6a19\u304c\u8abf\u6574\u30aa\u30c3\u30ba\u6bd4\u306e\u5834\u5408\uff08\u8abf\u6574\u30cf\u30b6\u30fc\u30c9\u6bd4\u306e\u5834\u5408\u306f \"HR\" \u3092\u6307\u5b9a\uff09\n  common = FALSE, # \u56fa\u5b9a\u52b9\u679c\u30e2\u30c7\u30eb\u3092\u9069\u7528\u3057\u306a\u3044\uff08\u5909\u91cf\u52b9\u679c\u30e2\u30c7\u30eb\uff09\n  random = TRUE # \u5909\u91cf\u52b9\u679c\u30e2\u30c7\u30eb\u3092\u9069\u7528\u3059\u308b\n)\n\n# \u7d50\u679c\u306e\u8868\u793a\nprint(meta_result)\n\n# \u30d5\u30a9\u30ec\u30b9\u30c8\u30d7\u30ed\u30c3\u30c8\u306e\u4f5c\u6210\nforest(meta_result)\n<\/code><\/pre>\n\n\n\n<p>\u4e0a\u8a18\u306e\u30b3\u30fc\u30c9\u3092\u5b9f\u884c\u3059\u308b\u3068\u3001\u7d71\u5408\u3055\u308c\u305fAOR\uff08\u307e\u305f\u306fAHR\uff09\u306895%\u4fe1\u983c\u533a\u9593\u3001\u7570\u8cea\u6027\u306e\u6307\u6a19\uff08$I^2$\u3001Q\u7d71\u8a08\u91cf\u306a\u3069\uff09\u304c\u8868\u793a\u3055\u308c\u308b\u3002\u307e\u305f\u3001\u30d5\u30a9\u30ec\u30b9\u30c8\u30d7\u30ed\u30c3\u30c8\u306b\u3088\u3063\u3066\u5404\u7814\u7a76\u306e\u7d50\u679c\u3068\u7d71\u5408\u7d50\u679c\u304c\u8996\u899a\u7684\u306b\u793a\u3055\u308c\u308b\u3002<\/p>\n\n\n\n<p><strong>\u5b9f\u884c\u7d50\u679c\uff1a<\/strong><\/p>\n\n\n\n<pre class=\"wp-block-code\"><code>> # \u7d50\u679c\u306e\u8868\u793a\n> print(meta_result)\nNumber of studies: k = 5\n\n                         OR           95%-CI    z  p-value\nRandom effects model 1.5550 &#91;1.2685; 1.9062] 4.25 &lt; 0.0001\n\nQuantifying heterogeneity (with 95%-CIs):\n tau^2 = 0.0347 &#91;0.0003; 0.4189]; tau = 0.1863 &#91;0.0163; 0.6472]\n I^2 = 64.6% &#91;7.0%; 86.5%]; H = 1.68 &#91;1.04; 2.72]\n\nTest of heterogeneity:\n     Q d.f. p-value\n 11.30    4  0.0234\n\nDetails of meta-analysis methods:\n- Inverse variance method\n- Restricted maximum-likelihood estimator for tau^2\n- Q-Profile method for confidence interval of tau^2 and tau\n- Calculation of I^2 based on Q\n> <\/code><\/pre>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><strong>\u30d5\u30a9\u30ec\u30b9\u30c8\u30d7\u30ed\u30c3\u30c8\uff1a<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"669\" height=\"230\" src=\"https:\/\/best-biostatistics.com\/toukei-er\/wp-content\/uploads\/2025\/07\/image-6.png\" alt=\"\" class=\"wp-image-4253\" srcset=\"https:\/\/best-biostatistics.com\/toukei-er\/wp-content\/uploads\/2025\/07\/image-6.png 669w, https:\/\/best-biostatistics.com\/toukei-er\/wp-content\/uploads\/2025\/07\/image-6-300x103.png 300w\" sizes=\"(max-width: 669px) 100vw, 669px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">\u7d50\u679c\u89e3\u91c8<\/h3>\n\n\n\n<p>\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306e\u7d50\u679c\u3092\u89e3\u91c8\u3059\u308b\u969b\u306b\u306f\u3001\u4ee5\u4e0b\u306e\u70b9\u306b\u6ce8\u76ee\u3059\u308b\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7d71\u5408\u52b9\u679c\u91cf<\/strong>: \u7d71\u5408\u3055\u308c\u305fAOR\u307e\u305f\u306fAHR\u306e\u5024\u81ea\u4f53\u304c\u3001\u66dd\u9732\uff08\u307e\u305f\u306f\u4ecb\u5165\uff09\u304c\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u4e0e\u3048\u308b\u5168\u4f53\u7684\u306a\u52b9\u679c\u3092\u793a\u3059\u3002\u4eca\u56de\u306e\u30c7\u30fc\u30bf\u3067\u306f 1.55<\/li>\n\n\n\n<li><strong>95%\u4fe1\u983c\u533a\u9593<\/strong>: \u7d71\u5408\u52b9\u679c\u91cf\u306e\u4fe1\u983c\u533a\u9593\u304c1\uff08AOR \u307e\u305f\u306f AHR\u306e\u5834\u5408\uff09\u3092\u8de8\u3044\u3067\u3044\u308b\u304b\u3069\u3046\u304b\u3092\u78ba\u8a8d\u3059\u308b\u3002\u4fe1\u983c\u533a\u9593\u304c1\u3092\u8de8\u304c\u306a\u3044\u5834\u5408\u3001\u7d71\u8a08\u7684\u306b\u6709\u610f\u306a\u95a2\u9023\u304c\u3042\u308b\u3068\u89e3\u91c8\u3055\u308c\u308b\u3002\u4e0a\u8a18\u306e\u4f8b\u3067\u306f 1.27-1.91 \u3067 1 \u3092\u307e\u305f\u3044\u3067\u3044\u306a\u3044\u3002<\/li>\n\n\n\n<li><strong>\u7570\u8cea\u6027<\/strong>: $ I^2 $ \u7d71\u8a08\u91cf\u306f\u3001\u5168\u3070\u3089\u3064\u304d\u306e\u3046\u3061\u7570\u8cea\u6027\u306b\u8d77\u56e0\u3059\u308b\u5272\u5408\u3092\u793a\u3059\u3002\u4e00\u822c\u7684\u306b\u3001$ I^2 $ \u304c25%\u672a\u6e80\u3067\u3042\u308c\u3070\u7570\u8cea\u6027\u306f\u4f4e\u3044\u300125%\uff5e50%\u3067\u3042\u308c\u3070\u4e2d\u7a0b\u5ea6\u300150%\u8d85\u3067\u3042\u308c\u3070\u9ad8\u3044\u3068\u5224\u65ad\u3055\u308c\u308b\u3002\u7570\u8cea\u6027\u304c\u9ad8\u3044\u5834\u5408\u306f\u3001\u305d\u306e\u539f\u56e0\u3092\u63a2\u7d22\u3059\u308b\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u89e3\u6790\u3084\u30e1\u30bf\u56de\u5e30\u306a\u3069\u306e\u8ffd\u52a0\u89e3\u6790\u3092\u691c\u8a0e\u3059\u308b\u3002\u4e0a\u8a18\u306e\u7d50\u679c\u306f\u300164.6 % \u3067\u7570\u8cea\u6027\u306f\u9ad8\u3044\u3068\u306e\u5224\u65ad\u306b\u306a\u308b\u3002<\/li>\n\n\n\n<li><strong>\u30d5\u30a9\u30ec\u30b9\u30c8\u30d7\u30ed\u30c3\u30c8<\/strong>: \u5404\u7814\u7a76\u306e\u70b9\u63a8\u5b9a\u5024\u3068\u4fe1\u983c\u533a\u9593\u3001\u305d\u3057\u3066\u7d71\u5408\u3055\u308c\u305f\u52b9\u679c\u304c\u8996\u899a\u7684\u306b\u8868\u793a\u3055\u308c\u308b\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u5404\u7814\u7a76\u306e\u3070\u3089\u3064\u304d\u3084\u7d71\u5408\u7d50\u679c\u3068\u306e\u6574\u5408\u6027\u3092\u78ba\u8a8d\u3067\u304d\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u307e\u3068\u3081<\/h2>\n\n\n\n<p>\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306b\u304a\u3051\u308b\u8abf\u6574\u30aa\u30c3\u30ba\u6bd4\u3084\u8abf\u6574\u30cf\u30b6\u30fc\u30c9\u6bd4\u306e\u7d71\u5408\u306f\u3001\u8907\u96d1\u306a\u624b\u9806\u3092\u4f34\u3046\u304c\u3001\u9069\u5207\u306a\u30c7\u30fc\u30bf\u6e96\u5099\u3068\u7d71\u8a08\u624b\u6cd5\u3092\u7528\u3044\u308b\u3053\u3068\u3067\u3001\u8cea\u306e\u9ad8\u3044\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u751f\u6210\u3067\u304d\u308b\u3002\u7279\u306b\u3001\u6a19\u6e96\u8aa4\u5dee\u306e\u8a08\u7b97\u3084\u5909\u91cf\u52b9\u679c\u30e2\u30c7\u30eb\u306e\u9078\u629e\u306f\u91cd\u8981\u306a\u30dd\u30a4\u30f3\u30c8\u3067\u3042\u308b\u3002\u672c\u8a18\u4e8b\u3067\u7d39\u4ecb\u3057\u305fR\u3092\u7528\u3044\u305f\u8a08\u7b97\u4f8b\u3092\u53c2\u8003\u306b\u3001\u305c\u3072\u3054\u81ea\u8eab\u306e\u7814\u7a76\u306b\u5fdc\u7528\u3055\u308c\u305f\u3044\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306f\u3001\u8907\u6570\u306e\u72ec\u7acb\u3057\u305f\u7814\u7a76\u7d50\u679c\u3092\u7d71\u5408\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u4fe1\u983c\u6027\u306e\u9ad8\u3044\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u5c0e\u304d\u51fa\u3059\u5f37\u529b\u306a\u624b\u6cd5\u3067\u3042\u308b\u3002\u7279\u306b\u3001\u8abf\u6574\u30aa\u30c3\u30ba\u6bd4 (Adjusted Odds Ratio: AOR) \u3084 \u8abf\u6574\u30cf\u30b6\u30fc\u30c9\u6bd4  [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":4253,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"swell_btn_cv_data":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[46],"tags":[],"class_list":["post-4248","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-46"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/best-biostatistics.com\/toukei-er\/wp-content\/uploads\/2025\/07\/image-6.png","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/posts\/4248","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/comments?post=4248"}],"version-history":[{"count":3,"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/posts\/4248\/revisions"}],"predecessor-version":[{"id":4255,"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/posts\/4248\/revisions\/4255"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/media\/4253"}],"wp:attachment":[{"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/media?parent=4248"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/categories?post=4248"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/best-biostatistics.com\/toukei-er\/wp-json\/wp\/v2\/tags?post=4248"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}