{"id":527,"date":"2018-07-30T20:37:06","date_gmt":"2018-07-30T11:37:06","guid":{"rendered":"https:\/\/best-biostatistics.com\/toukei-er\/entry\/how-to-determine-sample-site-in-case-control-studies\/"},"modified":"2024-10-21T13:58:38","modified_gmt":"2024-10-21T04:58:38","slug":"how-to-determine-sample-site-in-case-control-studies","status":"publish","type":"post","link":"https:\/\/best-biostatistics.com\/toukei-er\/entry\/how-to-determine-sample-site-in-case-control-studies\/","title":{"rendered":"R \u3067\u30b1\u30fc\u30b9\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u7814\u7a76\u306b\u5fc5\u8981\u306a\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3092\u8a08\u7b97\u3059\u308b\u65b9\u6cd5"},"content":{"rendered":"\n

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sample.size.case.control <-<\/span> function<\/span> (<\/span>f,<\/span> R,<\/span> alpha=<\/span>0.05<\/span>,<\/span> power=<\/span>0.8<\/span>){<\/span>\np3 <-<\/span> f*<\/span>R\/<\/span>(<\/span>1<\/span>+<\/span>f*<\/span>(<\/span>R-<\/span>1<\/span>))<\/span>\nq3 <-<\/span> 1<\/span>-<\/span>p3\nu <-<\/span> 1<\/span>\/<\/span>2<\/span>*<\/span>f*<\/span>(<\/span>1<\/span>+<\/span>R\/<\/span>(<\/span>1<\/span>+<\/span>f*<\/span>(<\/span>R-<\/span>1<\/span>)))<\/span>\nn <-<\/span> (<\/span>qnorm<\/span>(<\/span>alpha\/<\/span>2<\/span>,<\/span> lower.tail=<\/span>F<\/span>)<\/span>*<\/span>sqrt<\/span>(<\/span>2<\/span>*<\/span>u*<\/span>(<\/span>1<\/span>-<\/span>u))<\/span>+<\/span>qnorm<\/span>(<\/span>power)<\/span>*<\/span>sqrt<\/span>(<\/span>f*<\/span>(<\/span>1<\/span>-<\/span>f)<\/span>+<\/span>p3*<\/span>q3))<\/span>^<\/span>2<\/span>\/<\/span>(<\/span>f-<\/span>p3)<\/span>^<\/span>2<\/span>\nMETHOD <-<\/span> \"Case Control Study Sample Size Calculation\"<\/span>\nNOTE<\/span> <-<\/span> \"n is number in *each* group\"<\/span>\nstructure<\/span>(<\/span>list<\/span>(<\/span>n=<\/span>n,<\/span>\"Prop exposed in gen pop\"<\/span>=<\/span>f,<\/span> \"Assumed Odds Ratio\"<\/span>=<\/span>R,<\/span> sig.level=<\/span>alpha,<\/span> power=<\/span>power,<\/span> method=<\/span>METHOD,<\/span> note=<\/span>NOTE<\/span>),<\/span> class=<\/span>\"power.htest\"<\/span>)<\/span>\n}<\/span>\n<\/code><\/pre>\n\n\n\n
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><\/span> sample.size.case.control<\/span>(<\/span>f=<\/span>0.2<\/span>,<\/span> R=<\/span>5<\/span>)<\/span>\nCase Control Study Sample Size Calculation\nn =<\/span> 27.97932<\/span>\nProp exposed in<\/span> gen pop =<\/span> 0.2<\/span>\nAssumed Odds Ratio =<\/span> 5<\/span>\nsig.level =<\/span> 0.05<\/span>\npower =<\/span> 0.8<\/span>\nNOTE:<\/span> n is number in<\/span> *<\/span>each*<\/span> group\n<\/code><\/pre>\n\n\n\n
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><\/span> sample.size.case.control<\/span>(<\/span>f=<\/span>0.8<\/span>,<\/span> R=<\/span>3<\/span>)<\/span>\nCase Control Study Sample Size Calculation\nn =<\/span> 122.4343<\/span>\nProp exposed in<\/span> gen pop =<\/span> 0.8<\/span>\nAssumed Odds Ratio =<\/span> 3<\/span>\nsig.level =<\/span> 0.05<\/span>\npower =<\/span> 0.8<\/span>\nNOTE:<\/span> n is number in<\/span> *<\/span>each*<\/span> group\n<\/code><\/pre>\n\n\n\n
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><\/span> sample.size.case.control<\/span>(<\/span>f=<\/span>0.1<\/span>,<\/span> R=<\/span>2<\/span>)<\/span>\nCase Control Study Sample Size Calculation\nn =<\/span> 282.686<\/span>\nProp exposed in<\/span> gen pop =<\/span> 0.1<\/span>\nAssumed Odds Ratio =<\/span> 2<\/span>\nsig.level =<\/span> 0.05<\/span>\npower =<\/span> 0.8<\/span>\nNOTE:<\/span> n is number in<\/span> *<\/span>each*<\/span> group\n<\/code><\/pre>\n\n\n\n
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